Called into question in a March 29, 2012 scientific expose the reliability of highly-prestigious, highly-cited preclinical research
The researcher glut and scientific misbehaviors were exemplified in a devastating article published in the prestigious journal Nature on March 29, 2012. In it, researchers revealed that landmark, highly cited published studies on basic cancer research – many preclinical – were unreliable. Of 53 such studies identified, an astonishing 47 – 89 percent – could not be replicated. The article also cited a 2011 study by scientists at Bayer – titled "Believe It Or Not" – which found that of 47 cancer studies reviewed, less than one-quarter could be replicated. This grave problem is not limited to cancer experiments. One researcher told a National Academy of Sciences panel on March 27, 2012 that the fierce competition in academic institutions can result in poor science, even fraud, because too many researchers are competing for funds.
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